Having ovaries removed does not sound pleasant. More poignant perhaps is conditions like HNPCC in which carriers are almost assumed to get one or more cancers of the colon or other digestive/urinary/female reproductive tracts.

the odds of getting colon cancer in the general population is something like 1 in 16 occurring on average in one's 60's. If you have hnpcc it is something like 9 in 10 get colon cancer...on average in your mid 40's. It also tends to have faster onset.

People with hnpcc, at a minimum, get a colonoscopy every year. That is still no garantee, and it does nothing for the related kidney, bladder, endometrial, etc cancers that are linked to this genetic disorder. One approach carriers consider is removing their entire colon and rectum, and presumably living with a colostomy instead.

That is a drastic move!!!

In other words, a better predictive test to identify early stages would go a long way towards catching these cancers which are almost inevitable for the genetic carriers. Again, carriers usually start testing in their 20's and for the rest of their lives. It is terrifying. Imagine giving them some peace of mind that they might at least catch it early. Colon cancer at stage I is almost always cured by surgery, thereby avoiding radiation and chemotherapy.

We need better testing, as the CEA is a major crap shoot like the PSA.