(Tribune photo by Phil Velasquez/Kris Connor, Getty Images)

You can add Sean Penn to the long list of people who have been called out by Ozzie Guillen.

The outspoken White Sox manager called Penn a "payaso" (clown) and "izquierdista estupido" (stupid leftist) on Twitter Friday for his praise of controversial Venezuela President Hugo Chavez.

"Oh my God, Sean Penn defended our President Hugo Chavez," Guillen, a Venezuela native, tweeted. "That's easy when you [don't] live in Venezuela and have money. LOL...shame on [you]."

Penn appeared on HBO's "Real Time with Bill Maher" last week and was asked why he continues to defend Chavez.

"Every day this elected leader is called a dictator here, and we just accept it and accept it," Penn said. "And this is mainstream media, who should -- truly there should be a bar by which they -- one goes to prison for these kinds of lies."

Chavez addressed the Oscar-winning actor's comments during a televised rally in Venezuela's capital, Caracas (which has the highest murder rate in South America), on Wednesday.

"I was reading the declarations from our friend Sean Penn, the famous American actor," Chavez said. "Penn defended what he considers to be the truth."

Guillen, who received his U.S. citizenship in Jan. 2006, obviously disagreed.

"Oh God, you are very crazy," Guillen tweeted about Penn. "Go and move to our country. You will change your mind."