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Message: Ondine Highlights Successful Multi-Centre Gum Disease Trial Outcomes at Vancouve

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Ondine Highlights Successful Multi-Centre Gum Disease Trial Outcomes at Vancouve

posted on May 29, 08 06:09AM

Ondine Highlights Successful Multi-Centre Gum Disease Trial Outcomes at Vancouver Symposium

Thu May 29, 7:04 AM

VANCOUVER, May 29 /CNW/ - Ondine Biopharma Corporation (TSX: OBP; AIM: OBP), a medical technology company, today announced that it will be presenting clinical and scientific data on Periowave(TM) at a symposium being hosted by the Company on Thursday May 29, 2008 at the Morris J. Wosk Centre for Dialogue in Vancouver, B.C. Dr. Nicolas Loebel, the Company's Chief Technology Officer, will be presenting data on Photodisinfection, Periowave(TM) and results from the Canadian Multi-Centre Trial, a summary of which was initially released on May 7th 2008. Dr. Veronique Benhamou, DDS, Cert. Perio, a Periodontist and Director, Division of Periodontics, and Associate Professor at McGill University, Montreal Quebec, will be presenting case studies and discussing her clinical experiences with Periowave(TM) over the last two years.

In the Multi-Centre Trial, Periowave(TM) treatment resulted in significantly increased clinical attachment level (CAL, p=0.003) and reduced pocket depth (PD, p=0.01) when compared to Scaling & Root Planing (SRP) alone. In addition, 53% more diseased sites demonstrated full resolution of clinical symptoms and converted to a healthy state (Clinical Attachment Level (less than or equal to)3mm, p=0.0004) than was found using SRP alone. These results demonstrate that Periowave(TM) photodisinfection therapy can provide significant clinical benefits in patients with chronic adult periodontitis.

"We are proud to present the details of the Canadian Multi-Centre trial to clinicians and industry participants at this upcoming symposium," stated Carolyn Cross, President and CEO of Ondine Biopharma. "The multi-centre study represents the largest registered clinical trial of photodisinfection ever conducted, and we are pleased with the validation of these outcomes from the in-field experiences of clinicians such as Dr. Benhamou. These results provide further evidence that Periowave(TM) is an effective treatment modality for chronic periodontitis, a disease affecting over half of the adult population."



About The Canadian Multi-Center Trial



The Canadian Multi-Center Trial was a prospective, randomized, examiner-blinded study that included 121 patients and 4,500 defect treatment sites. Fifty-eight patients were included in the Periowave(TM) treatment arm and sixty-three patients were included in the control arm. The study was conducted at the University of Western Ontario, the University of Alberta, the University of Saskatchewan, and at a large private periodontal clinic in Toronto. More information about this trial can be found on the ClinicalTrials.gov website: http://clinicaltrials.gov/ct2/show/N...



About Periowave(TM)



Periowave(TM) is a photodisinfection system commercialized by Ondine that utilizes low-intensity lasers and microbiological stains to target and destroy microbial pathogens and reduce the symptoms of disease. The photodisinfection technology was developed by Professor Michael Wilson and colleagues at the Eastman Dental Institute, University College London, and licensed to Ondine by UCL Business plc, University College London. Periowave(TM) is currently approved in Canada and the European Union for several oral indications. Additional information about Periowave(TM) is available at www.periowave.com



About Ondine Biopharma Corporation



Ondine is developing non-antibiotic therapies for the treatment of a broad spectrum of bacterial, fungal and viral infections. The Company is focused on creating and commercializing leading edge products utilizing its patented light-activated technology. Photodisinfection provides broad-spectrum antimicrobial efficacy without encouraging the formation and spread of antibiotic resistance. The Company is headquartered in Vancouver, British Columbia, Canada, with a research laboratory in Bothell, Washington, USA, and an international office in St. Michael, Barbados. For additional information, please visit the Company's website at: www.ondinebiopharma.com.

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