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Ondine Announces Publication of Positive Results from Pseudomonas aeruginosa Era
Aug 07, 2008 05:34AM
Ondine Announces Publication of Positive Results from Pseudomonas aeruginosa Eradication Study Thursday August 7, 7:00 am ET
VANCOUVER, Aug. 7 /CNW/ - Ondine Biopharma Corporation (TSX: OBP; AIM: OBP), a medical technology company developing photodisinfection-based products, today announced that the results of a study using the Company's platform Photodisinfection technology to eliminate Pseudomonas aeruginosa will be published in the peer-reviewed journal Photochemistry and Photobiology.
P. aeruginosa is an opportunistic pathogen renowned for its ability to live in practically any environment, including distilled water or even some hospital disinfectant solutions. It is notorious for being resistant to almost all antibiotics, and it is often the source of intractable infections in cystic fibrosis patients where the fatality rate can approach 50%. In the recently published article entitled, "In Vitro Photodynamic Eradication of Pseudomonas aeruginosa in Planktonic and Biofilm Culture", Ondine researchers conclusively demonstrated rapid eradication of P. aeruginosa in both free-floating (planktonic) and the highly-resistant biofilm forms.
"We believe that Ondine's platform photodisinfection technology can scale to address numerous clinically unmet needs," stated Dr. Cale Street, Ondine's Director of Research. "Pseudomonads can cause dangerous infections in humans including respiratory infections, burn and wound infections, bacteremias, severe external ear infections, and bone and joint infections. Pseudomonads are one of the most difficult-to-kill microorganisms. Our photodisinfection technology has proven capable of eradicating this virulent pathogen in short time periods, without producing dangerous by-products. In addition, Photodisinfection does not induce the bacterial resistance factors that compromise antibiotics today. Our recent publication highlights the rigorous approach we take to research and development, and adds to the peer-reviewed literature available to our potential strategic partners for additional photodisinfection indications."