Thanks Bear, most of my thoughts are an amalgamation and assimimlation of what I have read here on Agora from you and MANY others, and appllying some of my own personal experience, and common sense. To be clear, I agree with your thinking, just being cautious, and grounded, waiting for data. Could just be my conservative defense mechanisms "protecting" me also lol

My biggest hesitation to rapid explosion is just the "under the radar" component you mentioned, but yeas that can all get obliterated by data and results quickly. Would love to see an Amarin-like jump, ... and that would just be the beginning ... the "ante ...

GLTA ... especially the people that have been on this for a few decades, bravely weathering the storm. VERY optimistic, just a tiny bit afraid to admit it lol