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Message: I asked IR today about why no aGFR data....

I was looking through the BETonMACE Cognitive Assessment study.  I noticed that the group that showed the most improvement (MoCA < 22 at baseline) also had a relatively high level of High Sensitivity C Reactive Protein (hsCRP) (4.4 mg/L (3.0-10.0).  Question: is there a correlation between high hsCRP and lower kidney function (eGFR)?  Or, has this already been addressed in previous posts?

 

I know that the MoCA <22 cohort showed the greatest improvement, and they also had the lowest overall eGFR at baseline.  I'm just trying to get a handle on the possible cause for the MoCA improvement: improved kidney function due to apabetalone; or improved (lowered)  hsCRP due to apabetalone. 

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