Something that gets lost on most of us that are frustrated with "failed" studies, is that we are on a frontier. Sometimes we don't know what we have without multiple studies, and sometimes we just don't know what we don't know. Failed studies in terms of meeting endpoints is a thing, and so is advancing the knowledge to refined and future successful endpoints, hopefully. Future development companies will have an easier time, on the back RVX exploring the frontier. We just need that first breakthrough. And a deal!!! :)