Toxicity

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Zenith's BET Inhibitor ZEN-3694 is Currently Being Evaluated in Multiple Oncology Clinical Trials

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jonzobot

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Toxicity

posted on Nov 02, 2022 03:10PM

It looks like one of the NCI trials has been discontinued due to unacceptable toxicity.

The trial was in Phase 1 for advanced or unresectable solid tumors with RAS alternations or TNBC, in comination with Binimetinib.

https://clinicaltrials.gov/ct2/show/NCT05111561

Another trial was suspended, "to address important protocol updates". Not sure what that means.

https://clinicaltrials.gov/ct2/show/NCT05372640?term=zen-3694&draw=3&rank=12

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