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Dear Agoracom Family,

I want to thank all of you for your patience with us over the past 48 hours and apologize for what was admittedly a botched launch of our new site.

As you can see, we have reverted back to the previous version of the site while we address multiple forum functionality flaws that inexplicably made their way into the launch.

To this end:

1.We have identified 8 fundamental but easily fixable flaws that will be corrected in the coming week, so that you can continue to use the forums exactly as you've been accustomed to.

2.Additionally we will also be implementing a couple of design improvements to "tighten up" the look and feel of the forums.

Sincerely,

George et al

Message: Clinical Trials
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JD had a great post on this last August about some of the considerations facing Bioasis for Phase 0 and Phase 1 trials. A Phase 0 trial should be relatively quick, since it is a small dose for a short time in a small number of patients. If it is a Phase 0 trial, such as is rumored for the Herceptin/Trastuzumab program (Mtfp-TZM), the trial should be relatively cheap and quick compared to a Phase 1. As for the LSD program, I am not sure if they'd be starting at Phase 0 or Phase 1 there....but the same considerations that JD brought up for Mtfp-TZM apply to the Mtfp-LSD program. Phase 1 would be much more expensive, take longer, require more compound and require more patients than a Phase 0. Without more detail from the company, it is hard to project costs/timelines.

BearDownAZ

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