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Zenith's BET Inhibitor ZEN-3694 is Currently Being Evaluated in Multiple Oncology Clinical Trials

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Message: Re: Zenith Announces Initiation of Phase 1b ZEN-3694 Trial

Re-posting a couple of my relevant posts from last week now that the offical news release is out.

Post 1: Looks like patients are now being invited to dance in ZEN-3694/Enzalutamide Combo Therapy trial. First site, UCSF, now recruiting. Nice timing, with the AGM/Corporate update coming in about a week. Could be interesting......

A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer

Post 2: It is quite possible that the single agent ZEN-3694 dose escalation portion is complete and they have now found the maximally tolerated dose for ZEN-3694. Based on previous trial timelines from other presentations, this likely triggered 1) the start of the ZEN-3694/enzalutamide combo trial dose escalation and 2) expansion of the single agent ZEN-3694 to a larger population of patients at the optimal dose. Based on the start of recruiting for the combo trial, we know that #1 is happening. We may not hear about #2 until the AGM/Corporate Update. As San Fran wrote, it sure would be nice to hear about how those prostate tumors responded during the dose escalation. 

BearDownAZ 

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