Aducanumab and the amyloid beta hypothesis is not dead yet!

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BearDownAZ

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Aducanumab and the amyloid beta hypothesis is not dead yet!

posted on Oct 22, 2019 09:09AM

Great article on this from John Carroll at EndPoints News.

UPDATED: In a stunning turnaround, Biogen says that aducanumab does work for Alzheimer's — after dredging data for positive outcomes

Biogen is banking on the high dose of aducanumab. Approval is not a slam dunk guarantee, but seems possible. Seems that high brain exposure is necessary to elicit the benefit. Sure seems like they would be interested in a little thing called xB3 to help them out with getting across the BBB.