Welcome to the Bioasis Technologies Hub On AGORACOM

Free
Message: Aposense

One of the Aposense Directors has a connection to Protalix (director)

This is what Aposense is all about:

The lack of efficacious and universal tools for Systemic Delivery of nucleic acids is widely-recognized as the major factor holding back clinical implementation of genetic drugs. The problem is that nucleic acids such as RNAi are relatively large and carry negative charges; therefore in order to take it across the cell’s membrane, very strong activation energy is required. Aposense’s Molecular Nano-Motors (MNMs) are rationally designed in order to break-down the Systemic Delivery barrier. These MNM are energized by the membrane dipole potential, a recently-discovered voltage, measurable in every leaflet of any phospholipid membrane. Due to the high hydrophobicity of biological membranes, the dipole potential translates into an enormously strong electric field of up to 1 billion V/m (!), spanning ~30 Å, from membrane surface to membrane center.

read more about Aposense

 

https://aposense.com/second-generation-motor/

 

Share
New Message
Please login to post a reply