Bear, 

you are right anything is possible in the trial, however had we hit 250 MACE events back in late November early december i would maybe think we are not getting the trial results desired for our TEST group, the longer this is taking the more confident Apabeatlone is doing exactly what the post hoc results from Assure trial showed, just maybe not as high on the 77% RRR since it was 5 point MACE, i am ok with 30 % or higher for 3 point mace. I hope the steering committee made the right changes to  the BETONMACE trial to get the results we need, The fact we have 8 DSMB reports is a huge confidence booster IMO, time will tell the market is telling us that this is not 100% , so i agree there are no guarantee but things are still looking good, all in my option!