Re: Seeming lack of interest
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Sep 12, 2019 06:41AM
Yes, that’s how apabetalone works, which makes good sense of course as a strategy to increase circulating HDL particle number. In contrast, the CETP inhibitors raise HDL cholesterol by putting the breaks on the transfer of CEs from HDLs to other lipoproteins. For another very good review article on this particular theme :
https://www.thelancet.com/journals/landia/article/PIIS2213-8587(19)30003-8/fulltext