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1.  Apabetalone supressing chemorisistance; interesting...

 

"Moreover, existing studies have reported that overexpressed ABCA1 facilitates tumor cell proliferation, tumor growth, and acquired chemotherapy resistance in multiple tumors [13,14,1518]. Yet treatment with inhibitor apabetalone ameliorates cell proliferation, tumor progression, and chemotherapy resistance."

Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma | European Journal of Medical Research | Full Text (biomedcentral.com)

 

2.  BETonMACE referenced in CRM syndrome burden - Review study

 

Humanistic and Economic Burden of Patients with Cardiorenal Metabolic Conditions: A Systematic Review | Diabetes Therapy (springer.com)

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