Re: BETonMACE Placebo Estimate
in response to
by
posted on
Feb 20, 2019 04:58PM
I don't recall Resverlogix ever explicitly stating the hypothesized mechanism by which apabetalone may synergize with rosuvastatin. I kind of recall them mentioning that it may have to do with effects of rosuvastatin on ABCA1 and reverse cholesterol transport. Here are a couple of references on that topic. Note, both are from the same investigator and the studies are done in mice.