Re: BETonMACE and Aminotransferases
in response to
by
posted on
Aug 14, 2019 02:34PM
Bear/Topcoin/BKC - Is it possible that those patients experiencing greater than 5X increase in ALTs are the ones that need it the most? My thought process here is that there may be so much low hanging fruit that apabetalone is able to pluck off the artery walls that the liver can't keep up to the increased load it is experiencing. Is it possible that future studies will include starting these patients that are having these larger increases in ALTs at much lower doses and increasing the amount and or frequency of dosing as thier bodies are able to deal with the increased load?
Thanks tada