,,well,,where the FDA has issued letters after the fact taking the opposite position from the understanding at such meetings, could it not be true for the reverse! I see a caveat where no epigenetic drug has been approved to date being an issue. But possibly the overall positiveness of data on multiple issues might just drag us across some sort of finish line.....or at least lesson the costs and time to complete validation of BET medicine......and as noted in a post previously the FDA is not the only food and drug administration world wide,,,,,7 billion of us are on this lonely rock in the cosmos...our data will be pointing on multiple fronts that the down regulation of inflammation is the key to our overall sucess..,and that is awesome,,,,,,just an opinion,,,,,